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HRP-3649 Recombinant Human NCAM2 Protein $250

Recombinant Human NCAM2 Protein

Product Name: Recombinant Human NCAM2 Protein
Catalog #:  HRP-3649
Manufacture:  LD Biopharma, Inc.

Human Neural Cell Adhesion Molecule 2 (NCAM2) gene encodes a receptor which play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons. NCAM2 is expressed most strongly in adult and fetal brain. 

Full-length extracellular domain of human NCAM2 cDNA (20 – 697aa) was constructed with codon optimization gene synthesis and expressed with a human alpha Fetal Protein N-terminal (AFPn) -His-TEV cleavage site Tag (217aa) fusion at its N-terminal in E.coli as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified.

Gene Symbol:  NCAM2 ( NCAM21 ) 
Accession Number:  NP_004531
Species:  Human
Package Size:  50 µg / Vial   
Composition: 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose, DTT and others.
Storage: In Liquid. Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days.
Key Reference:

Parcerisas A, et al.,NCAM2 Regulates Dendritic and Axonal Differentiation through theCytoskeletal Proteins MAP2 and 14-3-3. 

Cereb Cortex 30 (6), 3781-3799 (2020)

Rasmussen KK, et al.,NCAM2 Fibronectin type-III domains form a rigid structure thatbinds and activates the Fibroblast Growth Factor Receptor. Sci Rep 8 (1), 8957 (2018)

Winther M, et al., NCAM2/OCAM/RNCAM: cell adhesion molecule with a role in neuronalcompartmentalization. Int J Biochem Cell Biol 44 (3), 441-446 (2012)

  1. May be used for in vitro NCAM2 mediated neural cell differentiation regulation study in vitro using this recombinant NCAM2 protein either as soluble factor or as coating matrix protein. 
  2. May be used for NCAM2 protein-protein interaction assay.
  3. As native human NCAM2 immunogen for specific antibody production.
Quality Control: Purity: > 90% by SDS-PAGE.
Recombinant Protein Sequence:


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