Invention in the REGENERATIVE MEDICINE is what we do every day, benefits of patients is our final goal

Our Products

Home > Products

Cata #: Name of Product: Price:
HRP-3053 Recombinant YFP - Human ACE2 Fusion Protein $300

Recombinant YFP - Human ACE2 Fusion Protein

Product Name: Recombinant YFP - Human ACE2 Fusion Protein
Catalog #:  HRP-3053
Manufacture:  LD Biopharma, Inc.

The protein encoded by human angiotensin-converting enzyme 2 (ACE2) gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the ACE2 protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 ( COVID-19 virus ).


Full-length extracellular domain of human ACE2 cDNA (18 - 740aa, derived from BC039902) was constructed with codon optimization gene synthesis and expressed with YFP Protein as N-terminal (YFP: 256aa) fusion protein in E.coli as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified.

Gene Symbol:  

ACE2                          (ACEH ; UNQ868)

Accession Number:  NP_068576
Species:  Human
Package Size:  50 µg / Vial   
Composition: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose, DTT and others.
Storage: In Liquid. Keep at -80°C for long term storage. Product is stable at 4 °C for at least two weeks.
Key Reference:

Lu R, et al., Genomic characterization and epidemiology of 2019 novel coronavirus: implication for virus origins and receptor binding. Lancet. Feb 22: 395(10224): 565-574. (2020)


Zhang Q, et al., ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway. J. Exp. Clin. Cancer Res. 38 (1), 173 (2019)


Xu X, et al., RhoA-Rho associated kinase signaling leads to renin-angiotensin system imbalance and angiotensin converting enzyme 2 has a

protective role in acute pulmonary embolism. Thromb. Res. 176, 85-94 (2019)


Crackower MA, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417 (6891), 822-828 (2002)

  1. May be used for ACE2 protein-protein interaction assay, such as COVID spike protein and ACE2 binding assay.
  2. As native human ACE2 immunogen for its specific antibody production.
Quality Control: Purity: > 90 % by SDS-PAGE.
Recombinant Protein Sequence:


Download Datasheet