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HRP-1384 Recombinant Human Betatrophin Protein $300

Recombinant Human Betatrophin Protein

Product Name: Recombinant Human Betatrophin Protein
Catalog #:  HRP-1384
Manufacture:  LD Biopharma, Inc.

Human betatrophin is a secreted protein, which mainly expressed in human liver and fat tissues to regulate lipid metabolism and beta cell proliferation.

Full-length mature human Betatrophin cDNA ( 177aa ) was constructed with fully codon optimization strategy and expressed in non-fusion form as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified.

Gene Symbol:  Betatrophin (C19orf80, ANGPTL8; PRO1185; TD26; PVPA599) 
Accession Number:  NP_061157
Species:  Human
Package Size:  50 µg / Vial   
Composition: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, Sucrose and DTT.
Storage: In Liquid. Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days.
Key Reference: Peng Yi, et al., Betatrophin: A hormone that controls pancreatic b cell proliferation. Cell. 04.008 (2012)
Fu,Z., et al., Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family. Biochem. Biophys. Res. Commun. 430 (3), 1126-1131 (2013)
Quagliarini,F., et al., Atypical angiopoietin-like protein that regulates ANGPTL3. Proc. Natl. Acad. Sci. U.S.A. 109 (48), 19751-19756 (2012)

1. May be used for in vitro human Betatrophin signaling pathway regulation study for human pancreatic beta cell differentiation.

2. As antigen for specific antibody production.

Quality Control: Purity: > 90% by SDS-PAGE.
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