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| Cata #: | Name of Product: | Price: |
| HRP-1384 | Recombinant Human Betatrophin Protein | $300 |
| Product Name: | Recombinant Human Betatrophin Protein |
| Catalog #: | HRP-1384 |
| Manufacture: | LD Biopharma, Inc. |
| Intruduction: | Human betatrophin is a secreted protein, which mainly expressed in human liver and fat tissues to regulate lipid metabolism and beta cell proliferation. Full-length mature human Betatrophin cDNA ( 177aa ) was constructed with fully codon optimization strategy and expressed in non-fusion form as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified. |
| Gene Symbol: | Betatrophin (C19orf80, ANGPTL8; PRO1185; TD26; PVPA599) |
| Accession Number: | NP_061157 |
| Species: | Human |
| Package Size: | 50 µg / Vial |
| Composition: | 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, Sucrose and DTT. |
| Storage: | In Liquid. Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days. |
| Key Reference: | Peng Yi, et al., Betatrophin: A hormone that controls pancreatic b cell proliferation. Cell. 04.008 (2012)
Fu,Z., et al., Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family. Biochem. Biophys. Res. Commun. 430 (3), 1126-1131 (2013) Quagliarini,F., et al., Atypical angiopoietin-like protein that regulates ANGPTL3. Proc. Natl. Acad. Sci. U.S.A. 109 (48), 19751-19756 (2012) |
| Applications: | 1. May be used for in vitro human Betatrophin signaling pathway regulation study for human pancreatic beta cell differentiation. 2. As antigen for specific antibody production. |
| Quality Control: | Purity: > 90% by SDS-PAGE. |
| Recombinant Protein Sequence: | &MTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSGGSHHHHHHGSENLYFQGAPMGGPELAQHEELTLLFHGTLQLGQALNGVYRTTEGRLTKARNSLGLYGRTIELLGQEVSRGRDAAQELRASLLETQMEEDILQLQAEATAEVLGEVAQAQKVLRDSVQRLEVQLRSAWLGPAYREFEVLKAHADKQSHILWALTGHVQRQRREMVAQQHRLRQIQERLHTAALPA Download Datasheet |